AmeriHealth wants to ensure that our members receive drug therapy in a setting that is both cost-effective and safe for their clinical condition. Since January 1, 2012, AmeriHealth has considered the setting where commercial members can receive Ceredase^® (alglucerase), Cerezyme^® (imiglucerase), Soliris^® (eculizumab), and VPRIV^® (velaglucerase alfa). Effective July 1, 2012, as part of the precertification review process, AmeriHealth will consider the setting where eight additional infusion therapy drugs can be administered: Aralast NP (alpha-1 proteinase inhibitor [human]) Elelyso^® (taliglucerase alfa) Fabrazyme^® (agalsidase beta) Glassia (alpha-1 proteinase inhibitor [human]) Lumizyme^® (alglucosidase alfa) Myozyme^® (alglucosidase alfa) Prolastin^® (alpha-1 proteinase inhibitor [human]) These drugs will continue to be covered by AmeriHealth for members who meet the clinical criteria outlined in our medical policies, but only when the drugs are administered in the setting that is approved by AmeriHealth during the precertification review process. During this process, each member's unique medical needs and clinical history will be considered to determine which setting will be approved to receive drug therapy. AmeriHealth will also review any black box warnings included in the prescribing information at the time that precertification for the drug is requested. If there are clinical circumstances that require a member to receive one of these drugs in an outpatient facility, the provider must submit documentation to AmeriHealth that specifically addresses these clinical circumstances when submitting a request for coverage. To review the medical policies for the drugs listed, go to our Medical Policy website and type the name of the drug in the Search box.