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​Changes to medical policy on Pemetrexed (Alimta®), Pemetrexed (Pemfexy™)

October 7, 2022

​Effective November 7, 2022, AmeriHealth HMO, Inc., AmeriHealth Insurance Company of New Jersey, and AmeriHealth Administrators will update their medical policy on Pemetrexed (Alimta®), Pemetrexed (Pemfexy™) for Commercial members.

The medical necessity criteria will be revised to reflect the National Comprehensive Cancer Network (NCCN) compendia for Nonsquamous Non-Small Cell Lung Cancer (NSCLC) and Ovarian cancer, Fallopian Tube Cancer, and Peritoneal Cancer, including the additional indication of Malignant Peritoneal Mesothelioma (Sarcomatoid, Epithelioid, Biphasic, Benign Multicystic, Well-Differentiated Papillary) and Low-Grade Serous Carcinoma.

The following ICD-10 codes will be removed from this policy:

  • C34.00 Malignant neoplasm of unspecified main bronchus
  • C34.10 Malignant neoplasm of upper lobe, unspecified bronchus or lung
  • C34.30 Malignant neoplasm of lower lobe, unspecified bronchus or lung
  • C34.80 Malignant neoplasm of overlapping sites of unspecified bronchus and lung
  • C34.90 Malignant neoplasm of unspecified part of unspecified bronchus or lung
  • C56.9 Malignant neoplasm of unspecified ovary
  • C57.00 Malignant neoplasm of unspecified fallopian tube
  • C57.10 Malignant neoplasm of unspecified broad ligament
  • C57.20 Malignant neoplasm of unspecified round ligament
  • D15.0 Benign neoplasm of thymus

The following ICD-10 codes will be added to this policy:

  • C45.2 Mesothelioma of pericardium
  • C45.7 Mesothelioma of other sites
  • C45.9 Mesothelioma, unspecified

For more information, please refer to the policy notification published on October 7, 2022.


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