Each month, IBC features an example of how ICD-9 codes will translate to ICD-10 
codes. We will present coding examples from different specialties and popular 
disease categories to demonstrate the granularity that the new ICD-10 code set 
will provide.
Coding convention: New clinical concept in occurrence of 
drug toxicity (drug underdosing)
The coding examples will demonstrate the new clinical concept of drug 
underdosing conveyed in ICD-10.
Drug underdosing is a new clinical terminology in ICD-10. ICD-10 contains codes 
for underdosing, whereas ICD-9 does not. This term identifies situations in 
which a patient has taken less of a medication than prescribed by their 
physician or less than instructed by the manufacturer, whether inadvertently or 
deliberately.
For underdosing, assign the code from categories T36 – T50 found in 
Chapter 19. These codes require a 7th character extension to describe an 
initial encounter (A), subsequent encounter (D), or sequela encounter (S).
Underdosing codes must be identified in the following order:
The medical condition is sequenced first. The first-listed code would be the 
event that is triggered or prolonged due to this circumstance.
The underdosing code is listed as the secondary code assignment. Codes for 
underdosing should never be assigned as principal or first-listed codes.
The additional code explains why the patient is not taking the medication(s). 
Financial hardships and age-related debilities are some examples of underdosing.
  
Example A
A patient is prescribed the antibiotic tetracycline to treat a UTI (urinary 
tract infection). The patient did not take the medication as prescribed, which 
resulted in pyelonephritis (kidney infection).
ICD-10 Code
	Narrative
		Coding sequence
N10
	Acute tubulo-interstitial nephritis
		The first-listed code would be the event that is triggered or prolonged due to 
this circumstance.
T36.4x6A
	Underdosing of tetracyclines, initial encounter
		The underdosing code would be the secondary code assignment.
		 
Example B
		A patient is prescribed prednisone for rheumatoid arthritis and has been taking 
it long-term. The patient abruptly stopped taking the medication, which 
resulted in secondary adrenal insufficiency. The patient is aware of the risk 
of not being weaned from steroidal drugs but could not afford to pay for the 
medication.
		
ICD-10 Code
	Narrative 
		Coding sequence
E27.40
	Unspecified adrenocortical insufficiency
		The first-listed code would be the event that is triggered or prolonged due to 
this circumstance.
T38.0x6
	Underdosing of glucocorticoids and synthetic analogues 
		The underdosing code would be the secondary code
		assignment.
Z91.120
	Patient's intentional underdosing of medication regimen due to financial 
hardship
		The additional code explains why the patient is not taking the medication(s).
		Note: In this scenario, E27.3 (drug-induced adrenocortical insufficiency) would 
not be appropriate, as the condition is not drug-induced but is directly 
attributed to the abrupt discontinuation of the medication.
		A complete list of all ICD-10 coding examples featured to date can be found 
here:
		>> 
ICD-10 Spotlight: Know the codes booklet
		For additional information related to the IBC transition to ICD-10, please 
visit the 
ICD-10 section 
of our website.