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This is a reminder that as of January 1, 2015, the Centers for Medicare 
& Medicaid Services (CMS) National Correct Coding Initiative (NCCI) edits 
are applicable to claims submitted on the CMS-1500 claim form or through the 
837P transaction. Please refer to the following claim payment policies on NCCI 
edits:
- Commercial: #00.01.56a: National Correct Coding Initiative (NCCI) 
Code Pair Edits;
- Medicare Advantage: #MA00.041: National Correct Coding Initiative 
(NCCI) Code Pair Edits.
Access these policies on our 
Medical Policy Portal. Select 
Accept and Go to Medical 
Policy Online, and then select the 
Commercial or 
Medicare 
Advantage tab from the top of the page, depending on the version of the 
policy you'd like to view.
The CMS NCCI tables (Column 1/Column 2) are composed of code pair edits. 
These code pair edits identify services that are either a component of a more 
comprehensive code or two codes that should not be reported together. Procedure 
code pairs designated by CMS with an NCCI modifier indicator of 0 (zero) are 
not eligible to be reimbursed separately when reported on the same date of 
service for the same member when performed by the same provider. The NCCI edit 
identified in the CMS NCCI file for these procedure code pairs will be applied 
by Independence regardless of the presence of a modifier.
Modifiers 25 and ?X{EPSU} and 59
Procedure code pairs designated by CMS with an NCCI modifier indicator of 1, 
when clinically appropriate, are eligible to be reported with an appropriate 
modifier for separate reimbursement. The most frequently used modifiers are 25 
and ?X{EPSU} and 59.
- Modifier 25: Modifier 25 is required when a significant, separately 
identifiable Evaluation and Management (E&M) service is performed by the same 
physician on the same day of a procedure or other service. For example, if an 
E&M service was also performed on the same day as an administration of an 
immunization, the E&M service should be billed with the modifier 25.
- Modifiers ?X{EPSU} and 59: Modifiers ?X{EPSU} and 59 are required to 
indicate that a procedure or service is separate, distinct, or independent from 
other non-E&M services performed on the same day by the same physician.
For more detailed information regarding the appropriate use of these modifiers, 
please visit our 
Medical 
Policy Portal. Select 
Accept and Go to Medical Policy Online, and 
then select the 
Commercial or 
Medicare Advantage tab from the top 
of the page, depending on the version of the policy you'd like to view:
- Modifier 25:
- –Commercial: #03.00.06l: Modifier 25: Significant, Separately 
Identifiable Evaluation and Management Service by the Same Physician on the Day 
of a Procedure or Other Service;
- –Medicare Advantage: #MA03.003a: Modifier 25: Significant, 
Separately Identifiable Evaluation and Management Service by the Same Physician 
on the Day of a Procedure or Other Service.
 
- Modifiers ?X{EPSU} and 59:
- –Commercial: #03.00.08d: Modifiers XE, XS, XP, XU, 59;
- –Medicare Advantage: #MA03.005a: Modifiers XE, XS, XP, XU, 
59.
 Note: As communicated in the July 2015 edition of Partners in Health 
UpdateSM, providers should use the more specific ?X{EPSU} 
modifiers to accurately represent the circumstances that render non-E&M 
services as separate, distinct, or independent. However, modifier 59 can still 
be reported if the service cannot be more accurately reported with one of the 
four specific modifiers. Providers cannot append more than one of these 
modifiers (i.e., XE, XP, XS, XU, or 59) to a single procedure code. Claims 
submitted with any of these modifiers may be subject to retrospective review 
and audit if it is determined that providers are not using them in accordance 
with the billing requirements in our claim payment policies.
Please refer to the CMS NCCI Edit web page for procedure code pair 
edits and the associated modifier indicators.
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