When you prescribe a new medication to adults ages 65 and older, please keep 
in mind that certain medications have a greater potential for side effects. 
Patients in this age group are twice as likely as those younger than 65 to 
experience adverse drug events — and almost seven times as likely to be 
hospitalized from them.
 
Keep in mind the following when potentially prescribing these 
medications:
 
- High-risk medications. 
The National Committee for Quality Assurance (NCQA) developed the High Risk 
Medication (HRM) list through its HEDIS®* program. The Pharmacy 
Quality Alliance (PQA) has adapted and endorsed NCQA?s HRM measure. Working 
alongside the Centers for Medicare & Medicaid Services (CMS) to improve the 
quality of health care, PQA maintains a list of medications considered to be 
high-risk in older adults. This list is based on the ?Beer?s Criteria? from the 
American Geriatrics Society standard list for potentially inappropriate 
medication use in older adults. CMS measures the number of Medicare Advantage 
HMO and PPO members ages 65 and older who are receiving HRMs from the list. 
Using this information, CMS grades each health plan?s quality of care through 
its Stars† program. 
- Adverse drug events. Through the Beer?s Criteria, HRMs 
have been proven to put older patients at a higher risk for adverse drug 
events. For example, medications such as zolpidem, amitriptyline, estrogens, 
and glyburide place patients at a higher risk for drug-related toxicities and 
increased risk for falls and fractures. Looking at the criteria, we have an 
opportunity to minimize the use of these and other medications deemed 
high-risk. 
There is an even greater risk when a patient is on more than one medication 
considered an HRM. Careful and appropriate use of drugs in the senior 
population is a critical quality-of-care issue. For these reasons we suggest 
that you use caution when prescribing one or more drugs on the list to patients 
ages 65 and older.
 
View the complete list of HRMs here. Look for more 
information about HRMs in the January 2016 edition of Partners in Health 
UpdateSM.
 
*The Healthcare Effectiveness Data and Information Set 
(HEDIS) is an NCQA tool used by more than 90 percent of U.S. health plans to 
measure performance on important dimensions of care.
 
†Stars is a program developed by CMS to 
measure quality health care. Ratings are published annually to help educate 
consumers prior to enrollment decisions.